Publications

SELECTED PUBLICATIONS

Click for the full publication list: Google Scholar

# equal contribution; * corresponding author

B. Li#, R. Manan#, S. Liang#, A. Gordon, A. Jiang, A. Varley, G. Gao, R. Langer, W. Xue, D. Anderson C. Atyeo, T. Raimondo, A. Gordon, L. Rhym, G. Alter, R. Langer, D. Anderson*, A combinatorial library of biodegradable ionizable lipids enables efficient pulmonary delivery of mRNA and potent in vivo genome editing in lung epithelia, Nature Biotechnology, in revision.

B. Li#, A. Jiang#, I.Raji, C. Atyeo, T. Raimondo, A. Gordon, L. Rhym, G. Alter, R. Langer, D. Anderson*, Engineering dually-adjuvanted mRNA vaccines, Nature Biomedical Engineering, in revision

B. Li#, I. Raji#, L. Sun, T. Raimondo, A. Gordon, A. Varley, A. Jiang, R. Langer, D. Anderson*, Machine-learning guided high-throughput platform enables rapid design of biodegradable ionizable lipids for potent in vivo mRNA delivery, under review

B. Li#, A. Gordon#, R. Manan, R. Langer, D. Anderson*, Lipid nanoparticle in inhalable dry powders enable efficient pulmonary delivery of mRNA, under review

Z. Yuan#, B. Li#, W. Gu, S. Luozhong, R. Li, S. Jiang*, Mitigating the Immunogenicity of AAV-Mediated Gene Therapy with an Immunosuppressive Phosphoserine-Containing Zwitterionic Peptide, J. Am. Chem. Soc. 2022, https://doi.org/10.1021/jacs.2c09484. [link]

B. Li#, Z. Yuan#, P. Jain, Y. He, H. Hung, X. Lin, S. Jiang*, De novo design of functional zwitterionic biomimetic material for immunomodulation, Science Advances, 2020, 6, eaba0754. [link] Highlighted by Chemical & Engineering News

B. Li#, Z. Yuan#, Y. He#, H. Hung, Y. He, P. Jain, S. Jiang*, Zwitterionic nanoconjugate enables safe and efficient lymphatic drug delivery, Nano Letters, 2020, 20, 6, 4693-4699. [link]

Z. Yuan#, B. Li#, L. Niu, Y. He, P. McMullen, S. Jiang*, Zwitterionic peptide cloak mimics protein surfaces for protein protection, Angewandte Chemie International Edition, 2020, 59, 1-5. [link]

J. Zheng, L. Fan, S. Qin, H. Li, M. Sang, R, Li, Y. Xu, H. Chen, Z. Yuan*, B. Li*, A bio-responsive near-infrared fluorescent probes for facile and persistent live-cell tracking, Small, 2020, 2002211. [link] Highlighted by Materials Views

B. Li#, P. Jain#, J. Ma#, J. Smith, Z. Yuan, H. Hung, Y. He, X. Lin, K. Wu, S. Jiang*, Trimethylamine N-oxide derived zwitterionic polymers: a new class of ultralow fouling bioinspired materials, Science Advances, 2019, 5(6), eaaw9562. [link]

F. Wang, Z. Yuan, P. McMullen, R. Li, J. Zheng, M. Xu, Q. He, B. Li*, H. Chen*, Near-infrared-light-responsive lipid nanoparticles as an intelligent drug release system for cancer therapy, Chemistry of Materials, 2019, 31(11), 3948-56. [link]

B. Li, Z. Yuan, P. Zhang, A. Sinclair, P. Jain, K. Wu, T. Bai, S. Jiang*, Zwitterionic nanocages overcome the efficacy loss of biologic drugs, Advanced Materials, 2018, 30, 1705728. [link] Cover story of Advanced Materials; Highlighted by Materials Views, and the UW “2017-2018 year in review” News.

B. Li, Z. Yuan, P. McMullen, J. Xie, P. Jain, H. Hung, S. Xu, P. Zhang, X. Lin, K. Wu, S. Jiang*, A chromatin-mimetic nanomedicine for therapeutic tolerance induction, ACS Nano, 2018, 12(12), 12004-12014. [link] Highlighted by Science Translational Medicine, 2018, 10 (470), eaaw0521.

B. Li, J. Xie, Z. Yuan, P. Jain, X. Lin, S. Jiang*, Mitigation of inflammatory immune responses with hydrophilic nanoparticles, Angewandte Chemie International Edition, 2018, 57, 4527-31. [link] Highlighted by the UW News

B. Li, Z. Yuan, H. Hung, J. Ma, P. Jain, C. Tsao, J. Xie, P. Zheng, X. Lin, S. Jiang*, Revealing the immunogenic risk of polymers, Angewandte Chemie International Edition, 2018, 57, 14069-72. [link]

B. Li#, F. Wang#, L. Gui, Q. He, Y. Yao, H. Chen*, The potential of biomimetic nanoparticles for tumor-targeted drug delivery, Nanomedicine, 2018, 13 (16), 2099-2118. [link]

D. Chen#, B. Li#, S. Cai, P. Wang, S. Peng, Y. Sheng, Y. Gu*, H. Chen*, Dual targeting luminescent gold nanoclusters for tumor imaging and deep tissue therapy, Biomaterials, 2016, 100, 1-16. [link]

H. Chen#, B. Li#, M. Zhang, K. Sun, Y. Wang, K. Peng, Y. Gu*, Characterization of tumor-targeting Ag2S quantum dots for cancer imaging and therapy in vivo, Nanoscale, 2014, 6(21), 12580-90. [link]

H. Chen#, B. Li#, C. Wang, X. Zhang, Z. Cheng, X. Dai, Y. Gu*, Characterization of a fluorescence probe based on gold nanoclusters for cell and animal imaging, Nanotechnology, 2012, 24(5), 055704. [link]