Meet Our Team
Bowen Li
Principle Investigator
Assistant Professor, Leslie Dan Faculty of Pharmacy & Institute of Biomedical Engineering
Affiliate Scientist, Princess Margaret Cancer Centre - University Health Network
Canada Research Chair in RNA Vaccines and Therapeutics
POSITIONS
University of Toronto
Assistant Professor, 02/2022-present
Department of Pharmaceutical Sciences
Institute of Biomedical Engineering (cross-appointed)
Faculty Member, PRiME - Precision Medicine initiative
Faculty Member, Emerging & Pandemic Infections Consortium (EPIC)
Princess Margaret Cancer Centre - UHN
Affiliate Scientist, 01/2023-present
EDUCATION
2022, Postdoc, Chemical Engineering, MIT, Bob Langer & Daniel Anderson labs
2019, Ph.D., Bioengineering, University of Washington-Seattle, Shaoyi Jiang lab
SELECTED AWARDS AND HONORS
2022 Canada Research Chair in RNA Vaccines & Therapeutics (Tier 2), CIHR
2022 Gairdner Early Career Investigator Award (selected by Pieter Cullis, Drew Weissman, Katalin Karikó)
2022 Emerging Investigator Award, Journal of Materials Chemistry B
2022 J. P. Bickell Foundation Medical Research Award
2022 Emerging Voice in Drug Delivery, Advanced Drug Delivery Reviews
2022 Connaught New Researcher Award
2022 New Initiative and Innovation Award, University of Toronto
2021 BMES Career Development Award
2019 Baxter Young Investigator Award
2019 Schmidt Science Fellowship, Finalist
2019 College of Engineering Student Award for Outstanding Research
2019 Bioengineering Departmental Award for Excellence in Research and Translation
2018 Chinese Government Award for Outstanding Students Abroad
2017 RSC Soft Matter Award
2017 Graduate School Fund for Excellence and Innovation
PROFESSIONAL ACTIVITIES
2022-present Canada Graduate Scholarships-Doctoral (CGS D) Program Review Committee, CIHR
2022-present Scientific Advisory Board, mRNA-Based Therapeutics Searchlight Network
2022-present Associate Editor, Journal of Gene Medicine
2021-present Editorial Board, Clinical and Experimental Pharmacology and Physiology
Andrew Varley
PRiME Postdoctoral Fellow
Ph.D., Applied Biosciences, University of Ontario Institute of Technology, 2021
Andrew Varley enjoys exploring all areas of science and engineering. He began his studies in engineering and physics before a passion for biotechnology and life sciences. He earned a Master’s degree in microbial biochemistry and completed his PhD studies on biochemical and chemical biological studies of gene silencing (siRNA) mechanisms in the Desaulniers lab at Ontario Tech University. Andrew is a passionate teacher, having taught or tutored academics or music since the age of 15. He enjoys spending his free time playing the piano or guitar, snowboarding, riding his motorcycle, socializing with friends, or simply playing some videogames.
Yue (York) Xu
PRiME-UHN Postdoctoral Fellow
york.xu@utoronto.ca
Ph.D., Pharmaceutical Engineering, China Pharmaceutical University, 2022
Yue Xu received his Ph.D. degree in Pharmaceutical Engineering at China Pharmaceutical University. His research interests focus on Medicinal Chemistry and Biomedical Imaging. He has published first-author papers in peer-reviewed journals, including the Journal of Medicinal Chemistry, Journal of Advanced Research, Small, and ACS Sensors. In the Li lab, Yue is working on the de novo design of LNPs for RNA delivery.
Kevin Wang
PharmSci Graduate student
kevinchang.wang@mail.utoronto.ca
M.S., Molecular Genetics, University of Toronto, 2022
I am interested in engineering novel RNA molecular therapies using synthetic biology. I completed my BSc in biological sciences at the University of Alberta and my MSc in molecular genetics at the University of Toronto. My diverse research experiences include DNA poxvirus genetics, neuropsychology data acquisition, high-throughput DNA multiplexing technologies, and microfluidic device design and fabrication. In my free time, I enjoy cooking for my family, improving my fitness level, playing video games, and exploring the great outdoors.
Tiana Young
PharmSci Graduate student
B.S., Pharmaceutical Chemistry, University of Toronto, 2022
I'm very passionate about research and enjoy learning new things, especially in the field of novel therapeutic solutions. I earned my HBSc at the University of Toronto with a specialization in Pharmaceutical Chemistry and a minor in Immunology. My research experience includes studying the role of the immune system in mediating idiosyncratic drug reactions in the Uetrecht Lab and working on the development of electrochemical biosensors in the Kelley Lab. In my free time, I'm a tech enthusiast and hobby artist who loves to play video games, watch documentaries, and read a good book.
Shannon Tsai
PharmSci Graduate student, NSERC CGS-M Fellow
sntsai@uwaterloo.ca
B.S., Nanotechnology Engineering, University of Waterloo, 2022
I recently earned my BASc in Nanotechnology Engineering at the University of Waterloo, where I developed an interest in pursuing further research in nanomedicine. My undergraduate research experiences focused on developing plasmonic nanoparticles for biomedical applications and optimizing new methods of measuring the surface energy of micro- and nanoparticles. I also gained industry experience at Precision Nanosystems working on customized GMP systems for manufacturing RNA therapeutics and optimizing lipid nanoparticle formulations for mRNA vaccines. In my spare time, I enjoy reading, drawing, spending time at my cottage, and learning how to bake new desserts.
Alex Golubovic
PharmSci Graduate student, NSERC CGS-M Fellow
a.golubovic@mail.utoronto.ca
B.S., Nanotechnology Engineering, University of Waterloo, 2022
Alex is passionate about the targeted delivery of drugs using nanomedicine. He understands that when one’s health falters, it can be extremely debilitating and all-consuming. Thus, he hopes to pave the way for more effective disease treatments with his research. Alex recently graduated with a BASc in Nanotechnology Engineering at the University of Waterloo, primarily working on synthesizing and testing new polymer formulations for thermoplastic applications during his co-ops. He was also a nuclear engineering consultant at NPX. In his free time, Alex loves going to the gym, hiking, watching sports, and listening to psychology podcasts.
Jingan (Charles) Chen
BME Graduate student
charless.chen@mail.utoronto.ca
B.S., Neuroscience, University of Toronto, 2021
Shufen (Sophia) Xu
Visiting Student
shufen.xu@mail.utoronto.ca
M.D. candidate, Nanjing Medical University
Shufen Xu is an M.D. student in the Second Affiliated Hospital of Nanjing Medical University. Her research interests focus on IncRNA, cancer Immunotherapy, cell biology, and tumor angiogenesis.
Lab Alumni
Name
Anni Pan
Justin Keung
Kidus Estifanos Biru
Former Position
Research technician
NSERC-USRA summer student, 05/2022-08/2022
Visiting student
Current Position
Technician, RNA Medicine Core
UofT PharmD student
MPharm Student, University College London
Hooka
Lab mascot
Bothell Kindergarten, 2021-present
Favorite: Puppuccino, flirt pole
A furry mascot lab visit day - Woof! _Apr 2023 🐕
Christmas potluck- Happy holiday! _Dec 2022 🍲
Farewell to Kidus - Good luck with your new Journey! _Dec 2022 🇬🇧
Happy Mid-Autumn Festival! _Sept 2022 🥮
First Li lab retreat in Toronto island! _Sept 2022 🏝️
Li lab started from here! _Feb 2022 🔬